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Association of brain atrophy and masseter sarcopenia with 1-year mortality in older trauma patients

JAMA Aug 28, 2019

Tanabe C, Reed MJ, Pham TN, et al. - Using opportunistic computed tomography imaging, researchers examined the correlation of masseter sarcopenia and brain atrophy with 1-year mortality among trauma patients older than 65 years via a retrospective cohort study of 327 adults 65 years and older. Of 327 involved, 72 had sarcopenia only, 71 had brain atrophy only, 92 had both, and 92 had neither. Masseter sarcopenia and brain atrophy were both independently and cumulatively related to mortality in older trauma patients, following adjustment for age, comorbidity, complications, and injury features. These radiologic indicators were easily measured opportunistically via standard imaging software. The results could potentially lead conversations about prognosis and interventions with patients and their families, since brain atrophy and masseter sarcopenia may be prognostic factors in older adults impacted by trauma.

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