Urbina EM, Mendizábal B, Becker RC, et al. - In order to define the optimal blood pressure (BP) percentile related to left ventricular hypertrophy (LVH) in youth, researchers analyzed 303 adolescents (mean age 15.6 years, 63% white, 55% male) for the link of systolic BP (SBP) percentile, independent of obesity, on left ventricular mass index (LVMI). They also estimated the SBP percentile that best predicts LVH in youth. Using the mean of 6 measurements of SBP at 2 visits employing the 2017 guidelines, these adolescents were grouped as low-risk (L = 141, < 80th percentile), mid-risk (M = 71, 80– < 90th percentile), or high-risk (H = 91, ≥ 90th percentile) and SBP, anthropometrics, and echocardiogram were assessed in these people. Across groups, a rise in mean BP, LVMI, and prevalence of LVH was noted. After adjusting for covariates, SBP percentile continued to be a significant determinant of LVMI. For predicting LVH, the best balance between sensitivity and specificity was offered by the 90th percentile for SBP. They concluded that it is possible to find abnormalities in cardiac structure in youth at BP levels below those used to define hypertension.