Tsivgoulis G, et al. - Given that data from observational studies on how admission hyperglycemia (aHG) relates to outcomes in acute ischemic stroke (AIS) patients treated with intravenous thrombolysis (IVT) are inconsistent, particularly when stratified by diabetes mellitus (DM) history, so researchers evaluated the connection of aHG (≥144 mg/dl) with outcomes stratified by DM history utilizing propensity score matched (PSM) data from the SITS-ISTR Registry. In both non-diabetic (n=12,318) and diabetic (n=6,572) PSM subgroups, patients with and without aHG did not vary in baseline features. In both diabetic and non-diabetic AIS patients treated with IVT, findings suggested an association of aHG with unfavorable three-month clinical results.