Heshmati K, et al. - Researchers investigated the impact of bariatric surgery on tumor features, cancer treatment, and oncologic outcomes in this retrospective cohort study of 42 patients diagnosed with breast cancer following bariatric surgery (1989–2014). They matched the patients to 84 subjects with breast cancer (1984–2012) who did not have bariatric surgery, based on age, body mass index, menopausal status at the time of breast cancer diagnosis, and the date of cancer diagnosis. Compared to non-operated, obese controls, women who developed breast cancer following bariatric surgery presented at an earlier stage. Multivariate analysis revealed a continuous association of bariatric surgery status with reduced human epidermal growth factor receptor 2 overexpression (HER2+) breast cancers, signifying that bariatric surgery may influence breast cancer features and, possibly, tumor biology. Bariatric surgery was linked with trends toward lower cancer-specific and all-cause mortality at a mean follow-up of 5 years.