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Association of atopic dermatitis severity with learning disability in children

JAMA Jun 22, 2021

Wan J, Mitra N, Hooper SR, et al. - Through analyzing data of US participants registered in the Pediatric Eczema Elective Registry between November 1, 2004, and November 30, 2019, researchers intended to determine if there is an association between atopic dermatitis (AD) severity and learning problems in children with AD. The sample consisted of 2,074 children with physician-confirmed AD (1,116 girls [53.8%]; median [interquartile range] age, 16.1 [13.9-19.5] years at 10-year follow-up). According to this cross-sectional study, 169 participants with AD reported a diagnosis of a learning disability (LD). The authors discovered that worse AD severity was associated with a higher risk of reported LD, regardless of socioeconomic factors, AD onset age, or other related disorders. Although more prospective and mechanistic studies are needed to clarify the relationship between AD and learning, the findings suggest that children with more severe AD should be screened for learning difficulties in order to initiate appropriate interventions that can mitigate the consequences of an LD.

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