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Association of atopic dermatitis severity with learning disability in children

JAMA Apr 18, 2021

Wan J, Mitra N, Hooper SR, et al. - Researchers conducted this cross-sectional study to assess the correlation of atopic dermatitis (AD) severity with learning problems in children with AD. Between November 1, 2004, and November 30, 2019, data of US participants registered in the Pediatric Eczema Elective Registry (PEER), were analyzed. Among the 2,074 AD participants (1,116 girls [53.8%]; median [interquartile range (IQR)] age, 16.1 [13.9-19.5] years at 10-year follow-up), 169 (8.2%) reported a diagnosis of an learning disability (LD). The authors discovered that worse AD severity was linked to greater chances of reported LD, independent of socioeconomic characteristics, AD onset age, and other related disorders. Although more prospective and mechanistic studies are needed to clarify the relationship between AD and learning, the findings suggest that children with more severe AD should be screened for learning difficulties in order to initiate appropriate interventions that can mitigate the consequences of an LD.

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