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Association of antioxidants and vitamin D level with inflammation in children with atopic dermatitis

International Journal of Dermatology Apr 15, 2019

Daniluk U, et al. - To examine the relationship between CoQ10, vitamin D, retinol, and α-tocopherol serum levels and severity of atopic dermatitis (AD) in children, researchers estimated 29 kids of age 1 to 15 years. In subjects with severe AD (77.8%), low vitamin D concentration (<20 ng/ml) was chiefly noted when compared to children with mild or moderate AD (25%) or the control group (31.8%). A significant decline in the concentration of retinol was recorded in severe AD cases (median 1.32 μmol/l). Significantly raised platelet count (PLT), red blood cell distribution width (RDW), and eosinophil count (EO) were presented only in the group with severe AD. A correlation between retinol level and PLT, white blood count (WBC), total IgE, mean platelet volume (MPV), and also with a disease severity index, SCORAD was reported. But, the vitamin D level was noticed in correlation with MPV only.
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