Irvin S, Weiderpass E, Stanczyk FZ, et al. - Researchers sought to ascertain the role of ovulation-regulating hormones in the etiology of ovarian cancer via prospectively analyzing the correlation of anti-mullerian hormone, follicle stimulating hormone (FSH) and inhibin B with ovarian cancer risk. They performed an assessment of 370 women from the Janus Serum Bank, comprising 54 Type 1 and 82 Type 2 invasive epithelial ovarian cancers and 49 borderline tumors and 185 age-matched controls. They observed an association of inhibin B with heightened risk of ovarian cancer overall and with type 1 ovarian. No correlation of FSH with overall ovarian cancer risk was observed however, higher FSH was correlated with type 2 ovarian cancers. These findings imply a possibly different influence of gonadotropin exposure on the risk of ovarian cancer across subtypes.