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Association of ambient air pollution with age-related macular degeneration and retinal thickness in UK Biobank

British Journal of Ophthalmology Jan 29, 2021

Chua SYL, Warwick A, Peto T, et al. - In this cross-sectional study, researchers sought to investigate the correlations of air pollution with both self-reported age-related macular degeneration (AMD), and in vivo measures of retinal sublayer thicknesses. The sample consisted of 115,954 UK Biobank participants aged 40–69 years old. Ambient air pollution measures involved particulate matter, nitrogen dioxide (NO2) and nitrogen oxides (NOx). According to findings, greater exposure to PM2.5 was correlated with self-reported AMD, whereas PM2.5, PM2.5 absorbance, PM10, NO2 and NOx were all related to differences in retinal layer thickness.

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