Ovadia C, et al. - Researchers quantified the adverse perinatal effects of pregnancy intrahepatic cholestasis in women with increased concentrations of serum bile acid and determined whether the risk of stillbirth and preterm birth was associated with elevated concentrations of bile acid. When serum bile acids concentrations are of 100 μmol/L or more, the risk of stillbirth is increased in women with intrahepatic cholestasis of pregnancy and singleton pregnancies. Since most women with intrahepatic cholestasis of pregnancy have bile acids below this concentration, it is likely that they can be assured that the risk of stillbirth is similar to that of pregnant women in the general population if repeated bile acid tests are carried out until delivery.