Mori H, et al. - In 166 patients with type 2 diabetes (aged ≥30 years), researchers assessed the relationship of sarcopenia and dynapenia with accumulated advanced glycation end-products (AGEs), which accumulate in various tissues under chronic hyperglycemic conditions. In patients with sarcopenia and dynapenia, they saw significantly higher skin autofluorescence, which is the independent determinant of the skeletal muscle mass index, grip strength, knee extension strength, sarcopenia, and dynapenia. In patients with type 2 diabetes, accumulated AGEs could be a factor in the reduction of muscle mass and strength, resulting in sarcopenia and dynapenia.