Kim JT, Cho BH, Choi KH, et al. - Researchers conducted the study to analyze the rate at which the likelihood of a good outcome of endovascular stroke therapy (EVT) decays with time when qualified patients are selected by baseline diffusion-weighted magnetic resonance imaging (DWI-MRI) and whether ischaemic core size affects this rate. In this study of 985 patients (age 69 ± 11 years; male 55%) who underwent EVT based on selection via DWI-MRI, the chance of a good outcome after EVT nonlinearly reduced, with a steeper decline at earlier OTP than at later OTP. Differential effects of OTP on functional outcomes were observed by baseline DWI-ASPECTS categories. Therefore, different time-based and ischaemic core size strategies for EVT are needed.