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Association between thyroid function and risk of gestational diabetes mellitus in assisted pregnancies: A retrospective cohort study

Diabetes Research and Clinical Practice Dec 12, 2020

Li X, Zuo J, Li YH, et al. - In this study, the relationship between thyroid function and gestational diabetes mellitus (GDM) risk was evaluated in assisted pregnancies. Between February 2013 and October 2017, researchers screened 57,386 pregnant women treated, and 2,211 patients were retrospectively enrolled, and their data were examined based on quintile groups constituted based on serum thyroid-stimulating hormone (TSH), free thyroxine (FT4), and thyroid peroxidase antibody (TPOAb) levels. They examined the odds ratios of GDM by multivariate logistic regression, adjusted for maternal age and pre-pregnancy body mass index (BMI). In individuals with assisted pregnancies, TPOAb+ is an independent risk factor for GDM. For GDM, the higher TSH or lower FT4 levels, with TPOAb+ detection, are risk factors in assisted pregnancies.

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