Association between structure-function characteristics and visual field outcomes in glaucoma subjects with intraocular pressure reduction after trabeculectomy
Journal of Glaucoma Aug 16, 2020
Kadziauskienė A, Chua J, Baskaran M, et al. - In this investigation involving 87 candidates (91 eyes) who successfully underwent trabeculectomy, researchers ascertained if the preoperative structure-function relationship helps to predict visual outcomes at 1-year post-trabeculectomy. All eyes underwent optical coherence tomography imaging and visual field (VF) assessment using 30-2 standard automated perimetry preoperatively at baseline and postoperatively 1 year after trabeculectomy. Outcomes from multivariate and univariate analysis for VF 1 year after trabeculectomy demonstrated that a positive preoperative retinal nerve fiber layer thickness deviation from the structure-function model was found to be significantly linked to improved postoperative VF outcomes. Baseline VF MD and the presence of severe glaucoma were other significant factors. Characteristics derived from the baseline structure-function relationship have been found to be strongly linked to postoperative VF outcomes. Such results indicate that the structure-function relationship may potentially have a role in anticipating VF progression after trabeculectomy.
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