Abdelkarim AH, et al. - Researchers examined whether statin use is assiciated with perioperative mortality in patients undergoing aortobifemoral bypass (ABFB) for aortoiliac occlusive disease. Retrospective analysis of data of 4445 patients who had ABFB from the American College of Surgeons National Surgical Quality Improvement Program dataset revealed statin use in 3032 (68.2%) patients. Statins users were noted to be older and were more likely to be diabetic and hypertensive and to have a history of chronic obstructive pulmonary disease when compared with non-statin users. They observed 32% reduction in 30-day mortality among statin users after adjustment for patients' demographics (age, sex, race), comorbidities (diabetes, hypertension, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, dialysis, bleeding disorder), smoking, clinical presentation (claudication vs critical limb ischemia), and elective surgery status. This is the largest study to date that establishes lower 30-day mortality after ABFB for aortoiliac occlusive disease in association with preoperative statin use.