Jeong W, Joo JH, Kim H, et al. - Adherence to statin therapy is recommended for hyperlipidemia patients because a significant association exists between statin adherence and ischemic and hemorrhagic stroke risk.

• From the Korean National Health Insurance Service-National Sample Cohort, data of 128,052 and 129,390 participants with hyperlipidemia were obtained for examining the risks of ischemic and hemorrhagic stroke, respectively.

• Participants were split into categories by statin adherence, estimated as the proportion of days covered (PDC; poor, moderate, good).

• Higher risks of ischemic and hemorrhagic stroke were observed in participants with poor PDC vs those with good PDC (ischemic stroke: hazard ratio [HR]=1.09, hemorrhagic stroke: HR=1.37).

• A higher risk of ischemic stroke was evident in women with poor PDC vs those with good PDC (HR=1.17), while men with poor PDC had a higher risk of hemorrhagic stroke vs those with good PDC (HR=1.55).

• A higher risk of ischemic stroke was found in people with disabilities who had poor PDC vs those with good PDC (HR=1.55).