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Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: The Hisayama Study

Atherosclerosis Sep 04, 2020

Mihara A, Ohara T, Hata J, et al. - In a general Japanese population, researchers assessed the risk of cardiovascular disease (CVD) and its subtypes [including coronary heart disease and stroke] in correlation with serum glycated albumin (GA) levels. This study involved Japanese community-dwellers (n = 2,965; aged ≥ 40 years) who were followed prospectively for a median of 10.2 years (2002–2012). Using the enzymatic method, measurements of serum GA were obtained, and serum GA was categorized into quartiles. Findings demonstrated a significant correlation of higher serum GA levels with the development of CVD and its subtypes, even in persons not having diabetes or those exhibiting normal hemoglobin A1c levels, in a general Japanese population.

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