Lee MJ, Huang CW, Chen YL, et al. - This study was undertaken to investigate if SSRI use affected the risk of kidney cancer. Researchers applied data from Taiwan's National Health Insurance Research Database to perform a population‐based retrospective cohort study. In this study, 222,024 SSRI users and 221,361 SSRI nonusers were found after adjusting for gender, age, urbanization level, comorbidity, and medication use through propensity score matching. The correlations between the use of individual SSRIs and the risk of kidney cancer were assessed via a Cox proportional hazards model with 1‐ and 2‐year induction periods. These data support that SSRIs are correlated with reduced kidney cancer risk and demonstrate that citalopram and paroxetine have protective effects in depressed patients with kidney cancer.