Duan W, et al. - Experts assessed the link between polycyclic aromatic hydrocarbons and osteoporosis in this study involving 3,053 individuals aged ≥ 50 years who were drawn from National Health and Nutritional Examination Survey (2005–2014). A total of 577 patients with osteoporosis were included. Findings suggested an association of 3-hydroxyfluorene with decreased odd of osteoporosis, while a correlation between 2-hydroxyfluorene and increased odds of osteoporosis was noted. Among the eight polycyclic aromatic hydrocarbons metabolites, they noted an association of 3-hydroxyfluorene with decreased odds of osteoporosis after controlling socio-demographic status, body mass index, alcohol, previous fracture, parental fracture, glucocorticoid use, dietary calcium intake, smoking, and other polycyclic aromatic hydrocarbons metabolites.