Association between perioperative hypotension and delirium in postoperative critically ill patients: A retrospective cohort analysis
Anesthesia & Analgesia Mar 01, 2020
Maheshwari K, Ahuja S, Khanna AK, et al. - By performing this inquiry among 1,083 postoperative patients admitted directly from an operating room to the surgical intensive care unit, researchers investigated whether intraoperative and postoperative hypotension is related to critical care delirium. They evaluated delirium with the Confusion Assessment Method for Intensive Care Unit patients at 12-hour intervals. Delirium was present in 377 (35%) patients within the first 5 postoperative days in the surgical intensive care unit. A moderate link of intraoperative hypotension with higher odds of postoperative delirium was identified. Postoperatively, a 10 mm Hg decrease in the lowest mean pressure on every day in the critical care unit was found to be significantly related to a greater hazard of delirium, with an adjusted hazard ratio 1.12. Findings revealed the link of both intraoperative and postoperative hypotension with delirium among postoperative critical care patients. The extent to which these links are causal is not known, but to the extent that they are, hypotension prevention may aid decrease delirium.
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