Association between periodontitis and risk of Alzheimer's disease, mild cognitive impairment and subjective cognitive decline: A case-control study
Journal of Clinical Periodontology Oct 11, 2018
Holmer J, et al. - Authors sought to test the presumption that periodontal disease contributes to the elevated risk of mild cognitive impairment (MCI), subjective cognitive decline (SCD) and Alzheimer′s disease (AD). Findings suggested an association of the marginal periodontitis with early cognitive impairment and Alzheimer′s disease. Nonetheless, noncausal explanations were not precluded by the study design. Compared to the controls, poor oral health and marginal alveolar bone loss were more prevalent. They noted an association of the cases group with a generalized marginal alveolar bone loss, increased number of deep periodontal pockets and dental caries.
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