Association between NT‐proBNP and nocturia among community‐dwelling elderly males and females: A cross‐sectional analysis of the HEIJO‐KYO study
Neurourology and Urodynamics Oct 26, 2020
Okumura K, Obayashi K, Tai Y, et al. - This study was undertaken to evaluate the relationship between B‐type natriuretic peptide (BNP) and nocturia among community‐dwelling males and females. Researchers enrolled a sum of 1,096 participants (mean age 71.9 ± 7.1 years, 518 [47.2%] males) in the study. They recorded the number of nocturnal voids in a self‐reported urination diary, and nocturia was characterized as two or more voids per night. They assessed the daytime serum concentration of the N‐terminal fragment of the BNP precursor (NT‐proBNP). They conducted a multivariable logistic regression analysis to ascertain the relationship between NT‐proBNP and nocturia. This research demonstrated higher serum NT‐proBNP is significantly and independently correlated with the prevalence of nocturia in both males and females. This is an exploratory cross‐sectional study and the analyses are post hoc, so future study works are required to verify the causality and clinical value.
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