Sabio J, et al. - Researchers assessed 77 females to delineate the potential relationship between 25-hydroxyvitamin D [25(OH)D] deficiency and non-dipper pattern in subjects with systemic lupus erythematosus (SLE). They reported that 62% of cases were non-dippers with lower levels of 25(OH)D as compared to dippers (19.4±8.9 vs 25.9±10.1 ng/ml). They noted a correlation between the nocturnal decline of mean blood pressure (BP) and levels of 25(OH)D. They observed an inverse correlation between night-time systolic, diastolic as well as mean BP and the levels of 25(OH)D, but only night-time systolic BP after adjustment for age and body mass index. Independent relations of 25(OH)D levels and the use of mycophenolate with the non-dipper pattern in SLE cases were also recorded suggesting the contribution of vitamin D deficiency to the development of a non-dipper pattern in subjects with SLE.