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Association between neutrophil to lymphocyte ratio and carotid artery wall thickness in healthy pregnant women

European Journal of Obstetrics & Gynecology and Reproductive Biology Oct 22, 2020

Sonaglioni A, Esposito V, Caruso C, et al. - Researchers here investigated possible changes in common carotid artery (CCA) intima-media thickness (IMT) during normal pregnancy and in the postpartum period. Further, they correlated these changes with neutrophil-to-lymphocyte ratio (NLR) and red blood cells distribution width (RDW). In this prospective study of 73 consecutive healthy pregnant women (32.8 ± 4.9 yrs/old), they observed progressive increase in both NLR and RDW and likewise, significant increase in parameters of carotid dimensions. Decrease in all hematological and morphological changes occurred in the postpartum period. Based on findings, they suggest pregnancy to be a state of chronic mild inflammation and significant association of the progressive increase in NLR and RDW during normal pregnancy with CCA intimal-medial thickening.

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