Pan Y, Xu J, et al. - Appendicular skeletal muscle mass [ASM]/height ² was found to be positively correlated with bone mineral density (BMD) and negatively related to osteoporosis in patients with type 2 diabetes mellitus.

• The sample consisted of 192 women and 225 men with type 2 diabetes mellitus.

• ASM/height ² had a positive correlation with serum calcium and BMD, according to Spearman's correlation analysis.

• The authors discovered significant correlations between ASM/height ² and total lumbar spine, hip, and femur neck BMD in multivariate regression analysis.

• ASM/height ² was the best marker of osteoporosis, according to the receiver operating characteristic curve, with a cut-off value of 7.87 kg/m ² for men and 5.94 kg/m ² for women.

• The risk of osteoporosis increased 6.036-fold in men and 4.079-fold in women when these cut-off values were used to identify sarcopenia.