Perucho JAU, Wang M, Tse KT, et al. - This study was attempted to assess the correlations of histogram features of T2-weighted (T2W) images and apparent diffusion coefficient (ADC) with treatment response in locally advanced cervical cancer (LACC) following concurrent chemoradiotherapy (CCRT). Researchers retrospectively examined a total of 58 patients who had undergone a 4-week CCRT regimen with MRI prior to treatment (pre-CCRT) and after treatment (post-CCRT). They applied VOIs from two radiologists to evaluate observer repeatability in delineation and feature values at both time-points with the Dice similarity coefficient (DSC) and intraclass correlation coefficient. The findings revealed that ADC and T2W histogram features could be applied to track changes in LACC tumours undergoing CCRT. It was reported that post-CCRT ADC50 was correlated with treatment response with good observer repeatability.