Ikehara S, et al. - Researchers conducted a prospective cohort study of a total of 94,349 singleton pregnancies in order to assess how maternal alcohol consumption during pregnancy influence the risk of preterm delivery. Questionnaires detailing alcohol consumption during the first trimester and during the second and third trimesters were administered to the participants. The analysis revealed a four-fold higher risk of preterm delivery among pregnant women in correlation with heavy alcohol consumption (≥ 300 g ethanol/week) during the second and third trimesters.