Nagata JM, Ganson KT, Gorrell S, et al. - In a population-based cohort of young adults, researchers explored the longitudinal connection between legal performance-enhancing substances and subsequent use of anabolic-androgenic steroids. They assumed that legal performance-enhancing substance use in young adulthood would be correlated with subsequent anabolic-androgenic steroid use at 7-year follow-up. Usage of anabolic-androgenic steroids is linked to negative physiological (eg, cardiovascular, neuroendocrine, musculoskeletal, and renal) health outcomes. In addition, anabolic-androgenic steroids are related to mood and substance-use disorders, aggression, and violence. In the United States, the use of anabolic-androgenic steroids is commonly found among adolescents and is more prevalent among adolescent boys relative to adolescent girls nationwide.