Birmingham TB, et al. - Using a within-patient, between-knees study design, researchers assessed the correlation between dynamic knee load and pain by minimizing confounding. With minimized between-patient confounding, findings suggested a strong correlation between medial knee load and increased knee pain during walking. They noted an association of the peak knee adduction moment and knee adduction impulse (proxies for medial knee loading) with increased pain and these remained significant after controlling for radiographic disease severity.