Association between inflammatory biomarkers and neointimal response following elective implantation of the ABSORB bioresorbable vascular scaffold
Coronary Artery Disease Apr 17, 2019
Rampat R, et al. - Given that the ABSORB bioresorbable vascular scaffold (BVS), vs metal stent, is related to greater neointimal proliferation and thrombotic rate, researchers assessed the role of inflammatory biomarkers on neointimal proliferation in the setting of BVS implantation. Arterial blood samples were obtained from 30 patients, both prior to elective percutaneous coronary intervention with the ABSORB BVS and at 9-months follow-up. They used enzyme-linked immunosorbent assay to determine the levels of interleukin-6, soluble CD40 ligand, monocyte chemotactic protein-1 and C-reactive protein in plasma. According to findings, no chronic inflammatory response was elicited due to elective percutaneous coronary intervention with the ABSORB BVS. They also found that post-procedure degree of neointimal proliferation was independent of the pre-existing inflammatory environment.
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