Choudhury M, et al. - In people with cystic fibrosis (CF)-related diabetes, researchers analyzed HbA_1c as a predictor of risk for future development of CF-related diabetes and evaluated the correlation with the development of retinopathy. This investigation was carried out in 50 adults with CF, comparing oral glucose tolerance test results with HbA_1c values in anticipating the development of CF-related diabetes. The results of this 7-year retrospective longitudinal study indicated that severity of diabetic retinopathy was related to a higher HbA_1c and longer duration of CF-related diabetes. A connection was found between HbA_1c level and the future development of dysglycemia in CF based on oral glucose tolerance test and microvascular results. Although the current guidelines do not advocate the use of HbA_1c as a diagnostic tool for CF-related diabetes, it can be of clinical use in identifying people at risk of future CF-related diabetes development.