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Association between furosemide exposure and patent ductus arteriosus in hospitalized infants of very low birth weight

The Journal of Pediatrics May 21, 2018

Thompson EJ, et al. - Using the Pediatrix Medical Group Clinical Data Warehouse, experts scrutinized the connection between furosemide exposure and patent ductus arteriosus (PDA) in a large, contemporary cohort of hospitalized infants with very low birth weight (VLBW). From 2011 to 2015, they identified all inborn infants of VLBW <37 weeks of gestation discharged from the Neonatal Intensive Care Unit after the first postnatal week. Multivariable logistic regression was performed to evaluate the relationship between PDA and exposure to furosemide. It was concluded that furosemide exposure was not correlated with increased odds of PDA treatment in hospitalized infants of VLBW.
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