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Association between furosemide administration and outcomes in critically ill patients with acute kidney injury

Critical Care Mar 11, 2020

Zhao GJ, Xu C, Ying JC, et al. - Researchers utilized real-world data to determine the link between furosemide use and outcomes among critically ill patients with acute kidney injury (AKI). From the Medical Information Mart for Intensive Care-III database, they selected critically ill patients suffering from AKI. They matched patients receiving furosemide to those without diuretics treatment, applying propensity score matching. Improved short-term survival and recovery of renal function was achieved with furosemide administration in critically ill patients with AKI. The effectiveness of furosemide was particularly evident among patients with AKI UO (urine output) stage 2–3 degree. However, it displayed no effectiveness in patients with AKI SCr (serum creatinine) stage 2–3 and chronic kidney disease. The findings are required to be confirmed in randomized controlled trials.
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