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Association between fat mass index, fat-free mass index, and hemoglobin A1c in a Japanese population: The Tohoku Medical Megabank Community-based Cohort Study

Journal of Diabetes Investigation Dec 12, 2021

Takase M, Nakamura T, Hirata T, et al. - Findings demonstrate a positive association between fat mass index and HbA1c (glycated hemoglobin A1c) levels.

  • In this cross-sectional study of 3,731 men and 9,191 women aged 20 years or older, residing in Japan, who were not treated for diabetes, the relationship between fat mass index and fat-free mass index with HbA1c was investigated.

  • Multivariable models showed an association of a higher fat mass index with higher HbA1c levels in males and females in all fat-free mass index subgroups.

  • Fat free mass index was also identified to be linked with HbA1c concentrations when participants who had been pointed out to have diabetes were excluded.

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