Association between coronary dominance and acute inferior myocardial infarction: A matched, case-control study
BMC Cardiovascular Disorders Feb 08, 2019
Wang L, et al. - In this case-control study performed in the Second Affiliated Hospital of Xi’an Jiaotong University in Xi’an, China, researchers investigated the link between coronary dominance and the incidence of acute inferior myocardial infarction (MI). Participants were 265 patients with acute inferior MI and 530 age-matched and sex-matched controls, all recruited between January 2011 and November 2014. Patients with a history of coronary artery bypass graft surgery, chronic or systemic diseases (including hepatic failure, kidney failure, hypothyroidism and Grave’s disease), ventricular fibrillation, and known allergy to iodinated contrast agent were excluded. The LD group included patients with left- or co-dominant anatomies and the RD group included those with right-dominant anatomy. A significant difference was noted in the distributions of right dominance between the acute inferior MI group and control group (94.0% vs 87.9%). Right dominance was suggested to be a risk factor for the incident acute inferior MI, on univariable conditional logistic regression. Multivariate conditional logistic regression revealed the association of right dominance with the incidence of acute inferior MI, even after adjusting for baseline systolic blood pressure, heart rate, smoking status, diabetes mellitus, hypertension, hyperlipidemia, and family history of coronary artery disease.
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