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Association between contrast-induced nephrotoxicity and contrast enhanced computed tomography followed by endoscopic retrograde cholangiopancreatography

European Journal of Radiology May 22, 2020

Shinoura S, Tokushige A, Chinen K, et al. - Among patients with abdominal complaints, whether an increased risk of contrast-induced nephrotoxicity (CIN) may be seen due to endoscopic retrograde cholangiopancreatography (ERCP) done within 72 hours following contrast enhanced computed tomography (CECT), was investigated in this single-center retrospective cohort study. There were overall 1,457 patients with CECT, among those, 90 (6.2%) had ERCP within 72 hours following CECT, and CIN occurrence was noted in 93 (6.4%). Of those who developed CIN, persistent CIN was present in 10 (11%). Findings revealed that ERCP done within 72 hours following CECT and pre-CECT serum creatinine level >1.5 mg/dL were related to CIN development in this patient population.

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