Association between body iron status and leukocyte telomere length, a biomarker of biological aging, in a nationally representative sample of US adults
Journal of the Academy of Nutrition and Dietetics Dec 20, 2018
Liu B, et al. - In this nationwide, population-based, cross-sectional study, researchers used data from the National Health and Nutrition Examination Survey (NHANES; 1999-2002) to assess the link between serum ferritin concentrations—an indicator of body iron status—and leukocyte telomere length in US adults. Participants included 7,336 adults aged ≥ 20 years who had available data on serum ferritin levels and telomere length. By means of linear regression with survey weights, they estimated the link between serum ferritin levels and telomere length. They reported 10.9% and 17.6% prevalence of adults with high and low serum ferritin levels, respectively. They observed shorter telomeres in relation to high body iron status—a link that was specifically observed in adults aged ≥ 65 years.
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