Chiriacò M, et al. - In adult patients with type 2 diabetes, researchers explored the connections between blood pressure variability (BPV)—expressed as long term (visit-to-visit) and short term (ambulatory blood pressure monitoring [ABPM] and home blood pressure monitoring [HBPM])—and all-cause mortality, major adverse cardiovascular events (MACEs), extended MACEs, microvascular complications (MiC), and hypertension-mediated organ damage (HMOD). The study sample consisted of 377,305 patients. Variability of systolic blood pressure—but not diastolic blood pressure—was linked to significantly increased risks of all-cause mortality, MACEs, extended MACEs, and MiC. According to qualitative analysis, BPV was linked to the presence of HMOD expressed as carotid intima-media thickness, pulse wave velocity, and left ventricular hypertrophy. Overall, BPV may provide additional information than just mean blood pressure on the risk of cardiovascular disease in patients with type 2 diabetes.