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Association between asthma and periodontal disease: A systematic review and meta-analysis

Journal of Periodontology Evidence based | Oct 24, 2017

Moraschini V, et al. - Researchers aimed to determine the link between asthma and periodontal disease, via a systematic review and meta-analysis. Evidence robustly indicated an association between asthma and periodontal disease.

Methods

  • Researchers performed an electronic search without date or language restrictions in MEDLINE, Cochrane, Web of Science, and LILACS until May 2016.
  • They also performed manual search and in the grey literature.
  • The search process, data analysis, and quality assessment were performed by two independent reviewing authors.
  • Prospective and retrospective cohort studies, case-controls, and randomized clinical trials were eligible to be included in this analysis.

Results

  • As per data, the search and selection process yielded 21 studies, published between 1979 and 2017.
  • In the meta-analysis, a statistically significant difference was demonstrated for the parameters of gingival bleeding, plaque index, and gingival index for asthmatic participants with P<0.0001, P<0.0001, and P= 0.0005, respectively.

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