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Assessment of voice outcomes following surgery for thyroid cancer

JAMA Otolaryngology-Head & Neck Surgery Sep 27, 2019

Kovatch KJ, et al. - In this cross-sectional, population-based survey, researchers identified the prevalence, severity, and factors correlated with poor voice outcomes after surgery for differentiated thyroid cancer. To determine factors linked to abnormal voice, multivariable logistic regression and zero-inflated negative binomial analysis were conducted. The sample consisted of 2,325 patients aged 17 to 89 years. In 272 patients following thyroid cancer surgery, abnormal voice was observed. The researchers noted a high prevalence of abnormal voice per Voice Handicap Index (VHI-10) validation, highlighting the necessity for increased awareness of voice abnormalities after surgery. The researchers also suggested that these findings warrants discussion of risk-benefit, the planned extent of surgery, and postoperative rehabilitation. In multivariable analysis, factors including age (45 to 54 years), black and Asian races, gastroesophageal reflux disease, and lateral neck dissection were linked to abnormal VHI-10 score.

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