Assessment of trends in transplantation of liver grafts from older donors and outcomes in recipients of liver grafts from older donors, 2003-2016
JAMA Surgery Feb 16, 2019
Haugen CE, et al. - Researchers sought to determine the trends in use of liver grafts from older donors (aged ≥70 years) and outcomes in liver-only transplant recipients of older donor grafts in the United States from 2003 to 2016. In this cohort study of 4127 liver grafts from older donors and 3350 liver-only recipients of older donor grafts, and 78 990 liver grafts from younger donors (aged 18-69 years) and 64 907 liver-only recipients of younger donor grafts, despite significant improvements in all-cause graft loss and mortality among liver transplant recipients of older donor grafts, a decrease in the use of liver grafts from older donors was observed. These findings justify the expansion of the donor pool through broader use of liver grafts from older donors.
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