Zahedi M, Kazemian E, Ramezani-Tehrani F, et al. - In this prospective study, researchers sought to determine the effect of the interaction between thyroid disorders, including hypothyroidism and/or thyroid autoimmunity, and gestational diabetes (GDM) on the incidence of type 2 diabetes (T2DM) among members of a population-based cohort study, the Tehran Thyroid Study (TTS), over a median follow up of 12.5 years. One thousand eight hundred ninety-four non-diabetic women aged 20 to 60 years, with a history of at least one term delivery, without diagnosed hyperthyroidism were chosen at the initiation of the Tehran Thyroid Study (TTS). There was no synergistic connection between GDM and thyroid disorders on the incidence of T2DM. Women with a GDM history, however, were at higher risk of developing T2DM later in their life. The risk of T2DM occurrence is also rising as women age. Targeted healthcare systems and lifestyle modification are advised, considering the significant prevalence of T2DM.