Ropers FG, et al. - In this systematic review and meta-analysis, researchers assessed the diagnostic yield of magnetic resonance imaging (MRI) and computed tomography (CT) in children with isolated unexplained unilateral sensorineural hearing loss (USNHL) and examined the clinical relevance of these findings. Of the 1562 studies, 18 participants were included in the analysis with a total of 1504 candidates. According to findings, imaging provided insight into the cause of hearing loss in children with isolated unexplained USNHL at a pooled frequency of about 35% to 37%. However, none of these findings had therapeutic consequences, and only a small proportion of children, namely those with an enlarged vestibular aqueduct, were informed about prognosis and hereditary factors by imaging. There is no convincing evidence to support a strong recommendation for imaging in children presenting with USNHL at the moment. The advantages of imaging during shared decision making should be carefully balanced against the disadvantages.