Heidkamp J, Weijs WLJ, van Engen-van Grunsven ACH, et al. - In the present study, the researchers sought to evaluate the feasibility of MRI for the assessment of surgical resection margins in fresh oral squamous-cell carcinoma (OSCC) specimens. Using 3 T clinical whole-body MRI, ten consecutive tongue specimens containing OSCC were scanned. Data reported that the positive predictive values (PPV) and negative predictive values (NPV) for OSCC localization were 96% and 75%, and 87% and 79% for reader 1 and 2, respectively. The PPV and NPV for margins identification < 5 mm were 38% and 91%, respectively, 5% and 87% for reader 1 and 2. MRI correctly identified OSCC in fresh OSCC specimens with a high inter-reader agreement, but accurate assessment of the surgical margin status did not seem feasible yet.