Shakir NA, et al. - Researchers determined the predictors of renal deterioration (RD) in adult patients with multiple sclerosis presenting for evaluation of lower urinary tract symptoms, with baseline UDS and either serum creatinine or renal ultrasound, from a prospectively maintained database in this study. By strict criteria, researchers found that the RD rate in patients with NGB was low (3%) at intermediate-term follow-up, which had no correlation with UDS parameters. Using more liberal criteria, they identified detrusor overactivity (DO) to be related to deterioration, justifying the study of the impact of more aggressive control of DO in this population.