Xavier SA, et al. - The prognostic performance of Albumin–Bilirubin (ALBI) score was comprehensively analyzed in patients with liver cirrhosis complicated with upper gastrointestinal bleeding (UGIB) while comparing it with Child–Pugh (CP) and Model for End-stage Liver Disease (MELD) scores. It was noted that ALBI score accurately predicted both in-stay and 30-day mortality. On the other hand, CP and MELD scores could not predict these outcomes. A fair prognostic prediction performance was illustrated by all scores for first-year and global mortality. Hence, the ALBI score appeared to be particularly beneficial in the assessment of short-term outcomes, displaying a better performance compared to most commonly used scores.

Methods

• The scheme of this research was a retrospective unicentric study.
• Enrollees constituted consecutive adult patients with cirrhosis admitted for UGIB between January 2011 and November 2015.
• An evaluation was carried out of the clinical, analytical, and endoscopic variables and ALBI, CP, and MELD scores at admission were calculated.

Results

• This study comprised of 111 patients.
• As per the data, during the first 30 days of follow-up, 12 (10.8%) patients died, and during the first year of follow-up, another 10 patients died (first-year mortality of 19.8%).
• By comparing the 3 scores, for in-stay and 30-day mortality, only the ALBI score illustrated statistically significant results, with an area under the curve (AUC) of 0.80 (P < 0.01) for both outcomes.
• It was noted that for first-year mortality, AUC for ALBI, CP, and MELD scores were 0.71 (P < 0.01), 0.64 (P < 0.05), and 0.66 (P=0.02), respectively.
• On the other hand, for global mortality, AUC were 0.75 (P < 0.01), 0.72 (P < 0.01), and 0.72 (P < 0.01), respectively.
• Data did not unveil any notable variations in first-year mortality and global mortality on comparing the AUC of the three scores.