Assessment of occupational exposure and spectrum of contact sensitization in metalworkers with occupational dermatitis: Results of a cohort study within the OCCUDERM project
Journal of the European Academy of Dermatology and Venereology Jan 23, 2020
Schubert S, Brans R, Reich A, et al. - In the present study, the researchers examined occupational exposure and identified relevant occupational sensitizers in metalworkers with occupational dermatitis (OD), as well as assessed suitability of current German patch test recommendations for this occupational group. Occupational exposure of 230 metalworkers with suspected OD patch tested in the Departments of Dermatology in Göttingen and Osnabrück (both Lower Saxony, Germany) in 2012–2017 was documented by questionnaire as part of the OCCUDERM project. According to the results, the most important exposures were metalworking fluids (MWFs) and skincare products. Among MWF allergens, sensitizations to formaldehyde and formaldehyde releasers, colophony/abietic acid and monoethanolamine have been found most frequently. The identified occupational allergen spectrum could largely be verified. Patch testing with material from the workplaces of the patients is recommended in parallel with the baseline and MWF series in order not to miss relevant sensitizations. Diagnosed sensitizations may not always be linked to particular occupational exposures.
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