Sun GZ, et al. - Researchers sought to test and validate the overall performance of the novel Peguero-Lo Presti electrocardiographic criteria for diagnosing left ventricular hypertrophy (LVH) in a general population from China. A total of 10,614 permanent residents (≥35 years of age) were made to complete 12-lead electrocardiography (ECG) and echocardiography at the same visit. The Peguero-Lo Presti criteria demonstrated higher sensitivity but lower specificity than Cornell and Sokolow-Lyon voltage according to the recommended criteria. Thereby suggesting no superiority of the Peguero-Lo Presti voltage as a screening tool for LVH in Asian population. Changing the cutoff values of Cornell voltage, to obtain maximum sensitivity, could make it a better screening test for LVH compared to this new index.