Assessment of macular capillary perfusion in patients with inactive Vogt-Koyanagi-Harada disease: An optical coherence tomography angiography study
Graefe's Archive for Clinical and Experimental Ophthalmology May 06, 2020
Karaca I, Yılmaz SG, Afrashi F, et al. - In the present study, the researchers sought to evaluate macular capillary perfusion in patients with inactive Vogt-Koyanagi-Harada (VKH) disease by utilizing optical coherence tomography angiography (OCTA). In total, 51 eyes of 51 patients with inactive VKH (group 1, n = 23), mean ages were 39.9 ± 11.8 (range, 24–58), and healthy volunteers (group 2, n = 28), mean ages were 38.9 ± 8.5 (range, 29–51) years, had detailed eye examination including OCTA (RTVue-XR Avanti) scanning. Data reported that central retinal thickness and subfoveal choroidal thickness were 218.2 ± 39.4 μm and 195.6 ± 28.6 μm in group 1, whereas 243.5 ± 9.7 μm and 316.7 ± 20.1 μm in group 2, respectively. No statistically significant difference was found between groups regarding acircularity index, choriocapillaris flow area, and vessel flow density. A weak negative link was found between BCVA (logMAR) and parafoveal and perifoveal vessel densities in superficial capillary plexus and deep capillary plexus of group 1. In patients with inactive VKH disease, macular capillary perfusion was significantly reduced both in superficial capillary plexus and deep capillary plexus.
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