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Assessment of efficacy and safety of arterolane maleate–piperaquine phosphate dispersible tablets in comparison with artemether-lumefantrine dispersible tablets in pediatric patients with acute uncomplicated Plasmodium falciparum malaria: A phase 3, randomized, multicenter trial in India and Africa

Clinical Infectious Diseases Nov 02, 2017

Toure OA, et al. - This multicenter (India and Africa), comparative, parallel-group trial was undertaken to assess the efficacy of the fixed-dose combination dispersible tablet of arterolane maleate (AM) 37.5 mg and piperaquine phosphate (PQP) 187.5 mg in children. Researchers identified that when compared to artemether-lumefantrine, the efficacy and safety of fixed-dose combination of AM and PQP was similar for the treatment of uncomplicated P. falciparum malaria in pediatric patients.
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